Jerry Seinfeld honors Julia Louis-Dreyfus during the 21st Annual Mark Twain Prize for American Humor at The Kennedy Center. An outstanding lineup of entertainers gathered in the Kennedy Center Concert Hall to salute Julia Louis-Dreyfus, recipient of the 21st annual Mark Twain Prize for American Humor on October 21, 2018. The Prize, which is named to honor one of the world’s greatest humorists, was presented at a gala performance featuring some of the biggest names in comedy.